Difference between revisions 804160532 and 804795358 on enwiki

{{distinguish|Acetoin}}
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| Reference = <ref>''[[The Merck Index]]'', '''15th Ed.''' (2013), p. 13, [http://www.rsc.org/Merck-Index/monograph/mono1500000065 Acetone Monograph] '''65''', O'Neil: [[The Royal Society of Chemistry]].{{subscription needed}}</ref>
| ImageFileL1 = Acetone-CRC-MW-ED-dimensions-2D.png
(contracted; show full)
Acetone has been studied extensively and is generally recognized to have low acute and chronic toxicity if ingested and/or inhaled.<ref name= sids >{{cite journal | title = SIDS Initial Assessment Report: Acetone | publisher = Environmental Protection Agency | url = http://www.inchem.org/documents/sids/sids/67641.pdf}}</ref>  Acetone is not currently regarded as a [[carcinogen]], a [[mutagen]]ic chemical or a concern for chronic [[neurotoxicity]] effects.<ref name="msds" />
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The materials safety data sheet for Acetone lists the following as Potential Health Effects. <br>

Inhalation: Inhalation of vapors irritates the respiratory tract. May cause coughing, dizziness, dullness, and headache. Higher concentrations can produce central nervous system depression, narcosis, and unconsciousness. <br>

Ingestion: Swallowing small amounts is not likely to produce harmful effects. Ingestion of larger amounts may produce abdominal pain, nausea and vomiting. <br>
Aspiration into lungs can produce severe lung damage and is a medical emergency. Other symptoms are expected to parallel inhalation. <br>

Skin Contact: Irritating due to defatting action on skin. Causes redness, pain, drying and cracking of the skin. <br>

Eye Contact: Vapors are irritating to the eyes. Splashes may cause severe irritation, with stinging, tearing, redness and pain. <br>

Chronic Exposure: Prolonged or repeated skin contact may produce severe irritation or dermatitis. <br>

Aggravation of Pre-existing Conditions: Use of alcoholic beverages enhances toxic effects. Exposure may increase the toxic potential of chlorinated hydrocarbons, such as chloroform, trichloroethane.<ref name="mids"/>

Acetone can be found as an ingredient in a variety of consumer products ranging from cosmetics to processed and unprocessed foods. Acetone has been rated as a [[generally recognized as safe]] (GRAS) substance when present in beverages, baked foods, desserts, and preserves at concentrations ranging from 5 to 8&nbsp;mg/L.<ref name= sids/>

====Toxicology====
(contracted; show full)[[Category:Biotechnology products]]
[[Category:Dialkylketones]]
[[Category:Ketone solvents]]
[[Category:Fuel additives]]
[[Category:Excipients]]
[[Category:Commodity chemicals]]
[[Category:GABAA receptor positive allosteric modulators]]
[[Category:Anticonvulsants]]