Revision 71762048 of "Laura Morelli" on itwikiNome = Laura Cognome = Morelli Sesso = F LuogoNascita = Sassari GiornoMeseNascita = 27 gennaio AnnoNascita = 1967 LuogoMorte = Torino GornoMeseMorte = 20 febbraio AnnoMorte = 2013 Attività = Antropologa fisica )) Ė stata ricercatore confermato nell' [[Università degli Studi di Sassari]] ==Biografia== Curriculum vitae et studiorum 2011 Nata a Sassari, Italia, il 27 gennaio 1967 Laureata in Scienze Biologiche (11-07-1992) - Università di Sassari Abilitazione all'esercizio della professione di biologo (1994) - Università di Sassari Dottore di Ricerca in Scienze Antropologiche (1996) - Università di Cagliari Posizioni Università di Sassari, Istituto di Microbiologia e Virologia (1992-1993) Tirocinio abilitante Università di Cagliari, Dipartimento di Biologia sperimentale (1993-1995) Dottoranda Universitat Autonoma de Barcelona, Unitat d’Antropologia (1994) Borsista Erasmus. CNR, Istituto di Genetica Molecolare, Alghero (1996-1998) Borsista CNR Università di Sassari, Dipartimento di Zoologia e Antropologia biologica (1998 – 2002) Assegnista di ricerca Università di Sassari, Clinica Neurologica (2002) Contrattista. Università di Cagliari, Ospedale Microcitemico (2003) Contrattista. Università di Sassari, Dipartimento di Scienze Biomediche (2004-2008) Assegnista di ricerca. Università di Sassari, Dipartimento di Zoologia e Genetica Evoluzionistica (2008-12) Ricercatore (BIO/18 - Genetica) Università di Sassari, Dipartimento di Scienze della Natura e del Territorio (dal 2012) Ricercatore (BIO/18 - Genetica) Attività didattica Professore aggregato di Genetica Medica per Biotecnologie (4CFU), Genetica Medica per Medicina e Chirurgia (5CFU) Interessi di ricerca Gruppo di Ricerca: Genetica Evoluzionistica Variabilità del DNA mitocondriale e del cromosoma Y in popolazioni umane e altri organismi Studi di associazione per la dissezione di varianti di suscettibilità a tratti multifattoriali Analisi degli effetti della selezione sul genoma umano Studio biodemografico in popolazioni umane mediante l'analisi dei cognomi ==Pubblicazioni== Principali pubblicazioni Sanna D, Pala M, Cossu P, Dedola GL, Melis S, Fresu G, Morelli L, Obinu D, Tonolo G, Secchi G, Triunfo R, Lorenz JG, Scheinfeldt L, Torroni A, Robledo R, Francalacci P. Mendelian breeding units versus standard sampling strategies: Mitochondrial DNA variation in southwest Sardinia. Genet Mol Biol. 2011 Apr;34(2):187-94. Epub 2011 Apr 1. PubMed PMID: 21734814; PubMed Central PMCID:PMC3115307. Francalacci P, Morelli L, Useli A & Sanna D. The History and Geography of the Y Chromosome SNPs in Europe: an update. JASs 2010 88:207-214 Sanna S, Pitzalis M, Zoledziewska M, Zara I, Sidore C, Murru R, Whalen MB, Busonero F, Maschio A, Costa G, Melis MC, Deidda F, Poddie F, Morelli L, Farina G, Li Y, Dei M, Lai S, Mulas A, Cuccuru G, Porcu E, Liang L, Zavattari P, Moi L, Deriu E, Urru MF, Bajorek M, Satta MA, Cocco E, Ferrigno P, Sotgiu S, Pugliatti M, Traccis S, Angius A, Melis M, Rosati G, Abecasis GR, Uda M, Marrosu MG, Schlessinger D, Cucca F. Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis. Nat Genet. 2010 May 9. PubMed PMID: 20453840. Morelli L, Contu D, Santoni F, Whalen MB, Francalacci P, Cucca F. A comparison of Y-chromosome variation in Sardinia and Anatolia is more consistent with cultural rather than demic diffusion of agriculture. PLoS One. 2010 Apr 29;5(4):e10419. PubMed PMID: 20454687. Zoledziewska M, Costa G, Pitzalis M, Cocco E, Melis C, Moi L, Zavattari P, Murru R, Lampis R, Morelli L, Poddie F, Frongia P, Pusceddu P, Bajorek M, Marras A, Satta AM, Chessa A, Pugliatti M, Sotgiu S, Whalen MB, Rosati G, Cucca F, Marrosu MG. Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia. Genes Immun. 2009 Jan;10(1):15-7. Epub 2008 Oct 23. PubMed PMID: 18946483. Contu D, Morelli L, Santoni F, Foster JW, Francalacci P, Cucca F. Y-chromosome based evidence for pre-neolithic origin of the genetically homogeneous but diverse Sardinian population: inference for association scans. PLoS One. 2008 Jan 9;3(1):e1430. PubMed PMID: 18183308; PubMed Central PMCID: PMC2174525. Francalacci P, Morelli L, Underhill PA, Lillie AS, Passarino G, Useli A, Madeddu R, Paoli G, Tofanelli S, Calò CM, Ghiani ME, Varesi L, Memmi M, Vona G, Lin AA, Oefner P, Cavalli-Sforza LL. Peopling of three Mediterranean islands (Corsica, Sardinia, and Sicily) inferred by Y-chromosome biallelic variability. Am J Phys Anthropol. 2003 Jul;121(3):270-9. PubMed PMID: 12772214. Contu D, Morelli L, Zavattari P, Lampis R, Angius E, Frongia P, Murru D, Maioli M, Francalacci P, Todd JA, Cucca F. Sex-related bias and exclusion mapping of the nonrecombinant portion of chromosome Y in human type 1 diabetes in the isolated founder population of Sardinia. Diabetes. 2002 Dec;51(12):3573-6. PubMed PMID: 12453916. Morelli L, Paoli G, Francalacci P. Surname analysis of the Corsican population reveals an agreement with geographical and linguistic structure. J Biosoc Sci. 2002 Jul;34(3):289-301. PubMed PMID: 12117210. Angius A, Melis PM, Morelli L, Petretto E, Casu G, Maestrale GB, Fraumene C, Bebbere D, Forabosco P, Pirastu M. Archival, demographic and genetic studies define a Sardinian sub-isolate as a suitable model for mapping complex traits. Hum Genet. 2001 Aug;109(2):198-209. PubMed PMID: 11511926. Lampis R, Morelli L, Congia M, Macis MD, Mulargia A, Loddo M, De Virgiliis S, Marrosu MG, Todd JA, Cucca F. The inter-regional distribution of HLA class II haplotypes indicates the suitability of the Sardinian population for case-control association studies in complex diseases. Hum Mol Genet. 2000 Dec 12;9(20):2959-65. PubMed PMID: 11115839. Lampis R, Morelli L, De Virgiliis S, Congia M, Cucca F. The distribution of HLA class II haplotypes reveals that the Sardinian population is genetically differentiated from the other Caucasian populations. Tissue Antigens. 2000 Dec;56(6):515-21. PubMed PMID: 11169241. Morelli L, Grosso MG, Vona G, Varesi L, Torroni A, Francalacci P. Frequency distribution of mitochondrial DNA haplogroups in Corsica and Sardinia. Hum Biol. 2000 Aug;72(4):585-95. PubMed PMID: 11048788. Morelli L, Vona G, Varesi L, Memmi M, Autuori L, Calò CM. Finger dermatoglyphics in the Corsican population (France). Anthropol Anz. 1999 Dec;57(4):339-47. PubMed PMID: 10676570. Torroni A, Huoponen K, Francalacci P, Petrozzi M, Morelli L, Scozzari R, Obinu D, Savontaus ML, Wallace DC. Classification of European mtDNAs from an analysis of three European populations. Genetics. 1996 Dec;144(4):1835-50. PubMed PMID: 8978068; PubMed Central PMCID: PMC1207732. Vona G, Calò CM, Mameli GE, Marini E, Morelli L, Succa V, Casula S, Ristaldi MS. Variability of the CD4 and F13A1 short tandem repeats in Corsicans, Sardinians and Piaroa Indians. Gene Geogr. 1996 Apr;10(1):51-63. PubMed PMID: 8913722. Steri M, Morelli L, Pitzalis M, Zoledziewska M, Busonero F, Maschio A, Poddie F, Uda M, Schlessinger D, Cucca F, Sanna S. (2011) A genome-wide analysis of Sardinian population structure - ESHG 2011, Amsterdam, May 25-31 (Poster) – EJHG 19:2 p342-343. Sanna S, Pitzalis M, Zoledziewska M, Zara I, Sidore C, Murru R, Whalen Mb, Costa G, Melis Mc, Deidda F, Corrado L, Barizzone N, Poddie F, Morelli L, et al. (2010). Variants within the CBLB gene are associated with multiple sclerosis. In: The American Society of Human Genetics 60th Annual Meeting - November 2-6, 2010 Washington, DC. Washington, DC, November 2-6, 2010, p. 340 Poster #1089 Francalacci P, Sanna D, Morelli L, Contu D, Cucca F. (2004)The phylogeny of the Y chromosome and the peopling of Europe. 14th Congress of the European Anthropological Association, Komotini p-15. Contu D. Francalacci P, Cucca F. and Morelli L. (2003)The chromosome Y structure of the Sardinian population. Congress on “Genetic of complex diseases and isolated populations” Tortolì (NU) 23-30/05, 2003. Morelli L. and Francalacci P. (2002) Genetic distances inferred by surname analysis. Congrès International “Environnement et Identité en Mediterranée“, Corte (France), 2002. Francalacci P. and Morelli L. (2002) The peopling of three mediterranean islands (Corsica, Sardinia and Sicily) inferred by Y-chromosome biallelic variability. Congrès International “Environnement et Identité en Mediterranée“, Corte (France), 2002. Morelli L. and Francalacci P. (2000) The population history of Corsica and Sardinia: the contribution of archaeology and genetics (Chapter 19). In C. Renfrew and Katie Boyle eds. "Archaeogenetics: DNA and the population prehistory of Europe" The McDonald Institute for Archaeological Research, Cambridge 185-190, 2000. Melis P, Morelli L, Angius , Casu G, Ombra N, Casula S, Maestrale G.B, Piras D, Cabras S, Pirastu M. (1999) Demographic, Genealogical and genetic characterization of an isolated Sardinian micropopulation suitable for the study of complex traits. Annual Meeting of The American Society of Human Genetics – Chicago, 1999. Morelli L, Grosso M.G, Casula M, Francalacci P. Mitochondrial variability and the peopling of two Mediterranean Islands. (1999) The Third Biennial Euroconference of the European Human Genome Diversity Project: "Human Diversity in Europe and Beyond: Retrospect and Prospect". Cambridge, Great Britain, 9-13/9, 1999 Francalacci P, Morelli L, Loizedda A, Orrù S, (1998) Phylogenetic analysis of human mtDNA lineages in Northern Sardinia, Italy. 3rd Balkan Meeting on Human Genetics, O.15, p.52 , 1998. 11th Congress of the European Anthropological Association, Jena p-83, 1998. Francalacci P, Morelli L, Torroni A. (1997) Mitochondrial DNA variability in two South European Islands. HUGO EC Euroconference “Variation in the human Genome: Acquiring, Handling and Storing the Data” - Helsinki, Finland 12-16/09 1997. Morelli L, Melis P, Angius A, Casu G, Robledo R, Cabras S, Pirastu M. (1997) Searching for founders of multifactorial traits in Sardinia. Meeting on “Human Evolution” Cold Spring Harbor Laboratory, New York 4-8/10 1997. Torroni A, Petrozzi M, Huoponen K, Francalacci P, Morelli L, Obinu D, Moral P, Savontaus M.L, Wallace D.C, Scozzari R. (1995) Analysis of mtDNA variation in European populations indicates that nine haplogroups encompass almost all mtDNAs in Europe. HUGO Euroconference “Human Genome variation in Europe: DNA Markers”, Barcelona (Spain), 1995. Rappelli P, Fiori P.L, Morelli L, Cappuccinelli P (1993)Impairment of macrophagic functions after ingestion of Plasmodium falciparum. IX International Congress of Protozoology, Berlino (D), 1993. Francalacci P, Sanna D, Morelli L (2007) Le peuplement de les îles Tyrrhéniennes. In: E. Crubezy, M.Gibert (Eds) Le peuplement de la Méditerranée. Synthèse et questions d'avenir. Francalacci P, Sanna D, Morelli L (2007) The peopling of the Tyrrhenian islands from a genetic uniparental perspective (mtDNA and Y chromosome). In: C. Santos, M. Lima (Eds) Recent Advances in Molecular Biology and Evolution: Applications to Biological Anthropology. Research Signpost, Trivandrum (India) All content in the above text box is licensed under the Creative Commons Attribution-ShareAlike license Version 4 and was originally sourced from https://it.wikipedia.org/w/index.php?oldid=71762048.
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