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User:Barras/Ferrocene
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==Applications of ferrocene and its derivatives==
Ferrocene and its numerous derivatives have no large-scale applications, but have many niche uses that exploit the unusual structure (ligand scaffolds, pharmaceutical candidates), robustness (anti-knock formulations, precursors to materials), and redox (reagents and redox standards).

===Fuel additives===
Ferrocene and its derivatives are [[antiknock agent]]s used in the fuel for 
[[petrol engine]]s; they are safer than [[tetraethyl lead]], previously used.<ref>[http://www.osd.org.tr/14.pdf Application of fuel additives]</ref> It is possible to buy at [[Halfords]] in the UK, a petrol additive solution which contains ferrocene which can be added to [[unleaded petrol]] to enable it to be used in [[vintage car]]s which were designed to run on leaded petrol.<ref>{{US patent|4104036}}</ref> The [[iron]] containing deposits formed from ferrocene can form a [[conductive]] coating on the [[spark plug]] surfaces.

In [[Diesel fuel|diesel]]-fuelled engines, ferrocene reduces the production of [[soot]].

Ferrocene is available under multiple brand names, including [[Ferox (fuel additive)|Ferox]].

===Pharmaceutical===
Some ferrocenium salts exhibit anticancer activity, and an experimental drug has been reported which is a ferrocenyl version of [[tamoxifen]].<ref name = top2003 /> The idea is that the tamoxifen will bind to the [[estrogen]] binding sites, resulting in a cytotoxicity effect.<ref name=top2003>{{cite journal|author=S. Top, A. Vessières, G. Leclercq, J. Quivy, J. Tang, J. Vaissermann, M. Huché and G. Jaouen| title=Synthesis, Biochemical Properties and Molecular Modelling St(contracted; show full)[[pl:Ferrocen]]
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