Difference between revisions 439312308 and 439336104 on enwiki

< previous diff
next diff >
Zerona
{{cleanup|date=April 2011}}{{More footnotes|article|date=July 2011}}
'''Zerona''' is a low-level laser device applied for non-invasive body slimming of the waist, hips, and thighs.  It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse.  The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was granted 510k market(contracted; show full)er on human blood leukocytes |volume=50 |issue=5 |pages=862–6 |journal=Biofizika}}</ref><ref>{{cite journal |pmid=15129632 |year=2004 |last1=Vladimirov |first1=IuA |last2=Klebanov |first2=GI |last3=Borisenko |first3=GG |last4=Osipov |first4=AN |title=Molecular and cellular mechanisms of the low intensity laser radiation effect |volume=49 |issue=2 |pages=339–50 |journal=Biofizika}}</ref><ref name=pmid8570716>{{cite journal |pages=580–7 |doi=10.1111/j.1751-1097.1995.tb02388.x |title=P
HOTODYNAMICALLY GENERATED 3-β-HYDROXY-5α-CHOLEST-6-ENE-5-HYDROPEROXIDE: TOXIC REACTIVITY IN MEMBRANES and SUSCEPTIBILITY TO ENZYMATIC DETOXIFICATIONhotodynamically generated 3-β-hydroxy-5α-cholest-6-ene-5- hydroperoxide: toxic reactivity in membranes and susceptibility to enzymatic detoxification |year=1995 |last1=Geiger |first1=Peter G. |last2=Korytowski |first2=Witold |last3=Girotti |first3=Albert W. |journal=Photochemistry and Photobiology |volume=62 |issue=3 |pmid=8570716}}</ref> This highly reactive oxygen molecule participates in numerous pathways within a cell. However, as the concentration of ROS elevates a process known as [[lipid peroxidation]] can occur where ROS reacts with lipids found within cell membranes temporarily damaging them.<ref name=pmid16248161/><ref name=pmid(contracted; show full)evel Laser Irradiation: A Noncontrolled, Nonrandomized Pilot Study |journal=The American Journal of Cosmetic Surgery |volume=27 |issue=4 |pages=177–84 |url=http://www.erchonia.com/files/uploads/1/file/Jackson_Reduction%20in%20Cholesterol%20and%20Triglyceride%20Serum%20Levels%20Following%203LT_AJCS_2010.pdf}}</ref> Presently, clinical studies are on-going to elucidate the potential utility of this application.{{Citation needed|date=July 2011}}

== References ==
{{reflist}}

[[Category:Laser medicine]]