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Zerona
'''Zerona''' is a low-level laser device developed by Erchonia Corp. for non-invasive body slimming of the waist, hips, and thighs. It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse. The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was granted 510k market clearance{{jargon-inline|date=May2014}} by the [[Food and Drug Administration]] in 2010 indicated for use as a non-invasive dermatological aesthetic treatment for the reduction of circumference of hips, waist, and thighs. Zerona was the first aesthetic device to receive this indication by the FDA following the completion of a [[placebo-controlled]], randomized, [[double-blind]], multi-centered [[clinical trial]].  Clinical study participants randomly assigned to receive “active” or real treatment displayed an average loss of {{Convert|3.5|in|cm|(contracted; show full)significant clinical investigation to determine the ideal output parameters to ensure optimal efficacy and safety.  Studies evaluated Zerona’s interaction with individual to several million fat cells in order to determine the precise slimming setting. Zerona is a [[monochromatic]] semiconductor diode laser that emits 5 independent 635&nbsp;nm divergent beams.

== History ==
Initial trials for the Zerona began back in late 1998 in Cali, Colombia, by Dr. Rodrigo Neira and his wife Dr. Clara Neira at the 
[[Universidad Nacional de Colombia]].  They first applied the device as an adjunct to [[liposuction]] to reduce pain and inflammation commonly experienced after the invasive surgical procedure. In hopes of achieving better pain reduction they began applying LLLT prior to aspiration and surprisingly found that the subcutaneous fat appeared softer and easier to extract. Fascinated with this finding, Dr. Neira and his wife started performing histological investigations to determine why laser had this unique biological influence on fat tissue. Ut(contracted; show full)== References ==
{{reflist|2}}

==External links==
* [http://www.erchonia.com/ Erchonia Corp., Official Website]

[[Category:Laser medicine]]
[[Category:Management of obesity]]