Difference between revisions 607281629 and 607281850 on enwiki

'''Zerona''' is a low-level laser device developed by Erchonia Corp. for non-invasive body slimming of the waist, hips, and thighs. It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse. The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was granted 510k market clearance{{jargon-inline|date=May2014}} by the [[F(contracted; show full)he Zerona began back in late 1998 in Cali, Colombia, by Dr. Rodrigo Neira and his wife Dr. Clara Neira at the [[Universidad Nacional de Colombia]].  They first applied the device as an adjunct to [[liposuction]] to reduce pain and inflammation commonly experienced after the invasive surgical procedure. In hopes of achieving better pain reduction they began applying LLLT prior to aspiration and surprisingly found that the subcutaneous fat appeared softer and easier to extract. Fascinated with this finding, 
Dr.the Neira and his wifes started performing histological investigations to determine why laser had this uniqueits biological influence on fat tissue. Utilizsing [[scanning electron microscopy]] and [[transmission electron microscopy]], they observed the formation of transitory pores or openings in the protective membranes of adipocytes which enabled stored intracellular lipids to be released from enlarged fat cells. The term emulsification was applied to describe the laser-induced liberation of the stored lipids. The initial findings were later confirmed by three individual sites including the [[University of Singapore, ]], [[University of Mexico]], and the [[University of Chicago]]. These findings prompted the development of a device, the EML Laser, to assist in the surgical procedure, liposuction, with the intent to emulsify the fat thereby softening the area prior to aspiration.  A placebo-controlled, randomized, double-blind, multi-centered clinical study was performed to evaluate the clinical utility of this application as an adjunct to liposuction and found that laser therapy decreased operating room times, increased the volume of fat extracted, less force was required by the ph(contracted; show full)== References ==
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==External links==
* [http://www.erchonia.com/ Erchonia Corp., Official Website]

[[Category:Laser medicine]]
[[Category:Management of obesity]]