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Zerona
'''Zerona''' is a low-level laser device developed by Erchonia Corp. for non-invasive body slimming of the waist, hips, and thighs. It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse. The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was granted 510k market clearance{{jargon-inline|date=May2014}} by the [[F(contracted; show full)lt;ref>{{cite journal |pmid=1053185 |year=1975 |last1=Mester |first1=E |last2=Korényi-Both |first2=A |last3=Spiry |first3=T |last4=Tisza |first4=S |title=The effect of laser irradiation on the regeneration of muscle fibers (preliminary report) |volume=8 |issue=4 |pages=258–62 |journal=Zeitschrift fur experimentelle Chirurgie}}</ref> In turn, an increase in electron and proton transfer increases the quantity of ATP that is synthesized which can directly affect numerous intracellular proteins.

The 
upregulation[[Downregulation and upregulation|upregulation]] of ATP induced by laser therapy is also responsible for the increased production of a natural byproduct known as [[reactive oxygen species]] (ROS).<ref name=pmid16248161>{{cite journal |pmid=16248161 |year=2005 |last1=Klebanov |first1=GI |last2=Chichuk |first2=TV |last3=Osipov |first3=AN |last4=Vladimirov |first4=IuA |title=Роль продуктов перекисного окисления липидов в механизме действия лазерного облучения на лейкоциты крови человека |language=Russian |trans_title=The role of lipid peroxidation pro(contracted; show full)== References ==
{{reflist|2}}

==External links==
* [http://www.erchonia.com/ Erchonia Corp., Official Website]

[[Category:Laser medicine]]
[[Category:Management of obesity]]