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Zerona
'''Zerona''' is a low-level laser device developed by Erchonia Corp. for non-invasive body slimming of the waist, hips, and thighs. It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse. The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was cleared as a [[Medical device#Class II: General controls with special (contracted; show full)ournal |pages=271–8 |doi=10.1172/JCI7901 |title=Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice |year=2000 |last1=Gavrilova |first1=Oksana |last2=Marcus-Samuels |first2=Bernice |last3=Graham |first3=David |last4=Kim |first4=Jason K. |last5=Shulman |first5=Gerald I. |last6=Castle |first6=Arthur L. |last7=Vinson |first7=Charles |last8=Eckhaus |first8=Michael |last9=Reitman |first9=Marc L. |journal=Journal of Clinical Investigation |volume=105 |issue=3 |pmid=10675352 |pmc=377444
|display-authors=9 }}</ref> Therefore, preserving cell viability while restoring a lean state is an important strategy as adipocytes exert a protective action by releasing beneficial endocrine hormones. Zerona has been proven to restore a lean state adipocytes without inducing cell apoptosis. It is hypothesized that Zerona could serve as an adjunct to other dietary therapies to promote insulin sensitivity and reduce the risk of diabetes.  Zerona, based on histological evidence, has proven to reduce adipose tissue fat m(contracted; show full)== References ==
{{reflist|2}}

==External links==
* [http://www.erchonia.com/ Erchonia Corp., Official Website]

[[Category:Laser medicine]]
[[Category:Management of obesity]]