Difference between revisions 640825241 and 642163408 on enwiki'''Zerona''' is a low-level laser device developed by Erchonia Corp. for non-invasive body slimming of the waist, hips, and thighs. It has been shown to disrupt [[adipocyte]], or fat cell, membranes causing the release of stored [[lipids]] and fatty material, in turn, promoting adipocyte collapse. The device was first introduced to the market in 2008 as an [[off-label use]] device for slimming, but later was cleared as a [[Medical device#Class II: General controls with special (contracted; show full)ated with inflammation in adults? |volume=30 |issue=3 |pages=210–4 |journal=Journal of endocrinological investigation}}</ref> A rise in pro-inflammatory [[adipokines]] coupled with cytokine production may promote the onset of metabolic disorders like [[atherosclerosis]].<ref name=pmid19723556>{{cite journal |pmid=19723556 |year=2010 |last1=Galic |first1=S|last2=Oakhill |first2=JS |title=Adipose tissue as an endocrine organ |volume=316 |issue=2 |pages=129–39 |journal=Molecule Cell Endocrinology |doi=10.1016/j.mce.2009.0.018|doi_brokendate=2014-03-23 }} </ref> Positively correlated with increased adipose tissue size are pro-inflammatory factors: [[tumor necrosis factor-α]] (TNF-α), [[interleukin-6]] (IL-6), and [[C-reactive protein]]. Participating in [[paracrine]] and [[autocrine]] signaling, adipocyte impairment may account for metabolic dysfunction as adipose tissue communicates with multiple body systems including nervous, immune, skeletal, cardiovascular, and gastrointestinal.<ref name=pmid17021375/> Positive caloric intake can result (contracted; show full)== References == {{reflist|2}} ==External links== * [http://www.erchonia.com/ Erchonia Corp., Official Website] [[Category:Laser medicine]] [[Category:Management of obesity]] All content in the above text box is licensed under the Creative Commons Attribution-ShareAlike license Version 4 and was originally sourced from https://en.wikipedia.org/w/index.php?diff=prev&oldid=642163408.
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