Difference between revisions 786490904 and 786606593 on enwiki{{Infobox company | name = Frequency Therapeutics | logo = | type = | industry = [[Biotechnology]] | fate = | predecessor = <!-- or: | predecessors = --> | successor = <!-- or: | successors = --> (contracted; show full) The company is developing drugs aimed at regenerating [[Cochlea|cochlear]] cells, whose damage is often cause of hearing loss.<ref>{{cite journal |last1= McLeSheridan|first1=WillCormac|title=Interest rekindles in drug cocktails that reprogram cells|url=https://www.nature.com/nbt/journal/v35/n6/full/nbt0617-489.html|journal=[[Nature (journal)]]|volume= |issue= |pages= |doi= |access-date=16 June 2017}}</ref> The company and its researchers have identified inhibitors of [[GSK3B]] and [[Histone deacetylase|HDAC]] as successfully promoting the generation of cochlear cells in vitro.<ref>{{cite journal |last1=McLean|first1=Will|title=Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells|url=http://www.cell.com/cell-reports/pdf/S2211-1247(17)30136-5.pdf|journal=[[Cell (journal)|Cell]]|volume= |issue=|pages= |doi=10.1016/j.celrep.2017.01.066|access-date=16 June 2017}}</ref><ref>{{cite web |title=Frequency Therapeutics Announces a Revolutionary Small-molecule Approach to Restore Hearing Published in Cell Reports|last= |first= |date= |url=http://www.frequencytx.com/news-events/pr-02-21-2017.php|publisher=[[Frequency Therapeutics]]|access-date=16 June 2017|quote=}}</ref> ==See also== *[[Histone deacetylase inhibitor]] ==References== {{reflist}} ==External links== *[http://www.frequencytx.com/ Company website] {{biotech-stub}} [[Category:Companies based in Massachusetts]] [[Category:Companies established in 2015]] All content in the above text box is licensed under the Creative Commons Attribution-ShareAlike license Version 4 and was originally sourced from https://en.wikipedia.org/w/index.php?diff=prev&oldid=786606593.
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