Difference between revisions 786606593 and 796684599 on enwiki{{Orphan|date=August 2017}}⏎ ⏎ {{Infobox company | name = Frequency Therapeutics | logo = | type = | industry = [[Biotechnology]] | fate = | predecessor = <!-- or: | predecessors = --> | successor = <!-- or: | successors = --> | founded = <!-- if known: {{Start date and age|YYYY|MM|DD}} in [[city]], [[state]], [[country]] --> | founder = <!-- or: | founders = --> | defunct = <!-- {{End date|YYYY|MM|DD}} --> | hq_location_city = | hq_location_country = | area_served = <!-- or: | areas_served = --> | key_people = {{unbulleted list|David Lucchino|Robert Langer|Jeffrey Karp}} | products = | owner = <!-- or: | owners = --> | num_employees = | num_employees_year = <!-- Year of num_employees data (if known) --> | parent = | website = <!-- {{URL|example.com}} --> }} '''Frequency Therapeutics''' is a biotechnology company based in [[Woburn, Massachusetts|Woburn]], Massachusetts. The company was started in 2015 and its focus is developing drugs to treat [[Hearing loss|hearing loss]].<ref>{{cite news |last= |first= |date= |title=Gels to Repair Hearing Loss? Drugmakers Try New Ear Treatments|url=https://www.bloomberg.com/news/articles/2016-10-14/drugmakers-try-gels-gene-therapy-to-help-reverse-hearing-loss|work=[[Bloomberg L.P.|Bloomberg]]|location= |access-date= }}</ref><ref>{{cite news |last= |first= |date= |title=Could an injection reverse hearing loss? This Woburn startup thinks so|url=https://www.bostonglobe.com/business/2017/04/11/new-woburn-biotech-targets-hearing-loss-with-mit-partners-discoveries/LEmIDgqmYm8KimC4FfBdsM/story.html|work=[[Boston Globe]]|location= |access-date= }}</ref><ref>{{cite news |last= |first= |date= |title=Farmington Medical Startup Targets Hearing Loss With New Drugs|url=http://www.courant.com/business/hc-hearing-loss-startuprecovered-fri-may--5-084003-2017--20170505-story.html|work=[[Hartford Courant]]|location= |access-date= }}</ref> The company is developing drugs aimed at regenerating [[Cochlea|cochlear]]r cells, whose damage is often cause of hearing loss.<ref>{{cite journal |last1=Sheridan|first1=Cormac|title=Interest rekindles in drug cocktails that reprogram cells|url=https://www.nature.com/nbt/journal/v35/n6/full/nbt0617-489.html|journal=[[Nature (journal)|Nature]]|volume= |issue= |pages= |doi= |access-date=16 June 2017}}</ref> The company and its researchers have identified inhibitors of [[GSK3B]] and [[Histone deacetylase|HDAC]] as successfully promoting the generation of cochlear cells in vitro.<ref>{{cite journal |last1=McLean|first1=Will|title=Clonal Expansion of Lgr5-Positive Cells from Mammalian Cochlea and High-Purity Generation of Sensory Hair Cells|url=http://www.cell.com/cell-reports/pdf/S2211-1247(17)30136-5.pdf|journal=[[Cell (journal)|Cell]]|volume= |issue=|pages= |doi=10.1016/j.celrep.2017.01.066|access-date=16 June 2017}}</ref><ref>{{cite web |title=Frequency Therapeutics Announces a Revolutionary Small-molecule Approach to Restore Hearing Published in Cell Reports|last= |first= |date= |url=http://www.frequencytx.com/news-events/pr-02-21-2017.php|publisher=[[Frequency Therapeutics]]|access-date=16 June 2017|quote=}}</ref> ==See also== *[[Histone deacetylase inhibitor]] ==References== {{reflist}} ==External links== *[http://www.frequencytx.com/ Company website] ⏎ {{biotech-stub}}⏎ ⏎ [[Category:Companies based in Massachusetts]] [[Category:Companies established in 2015]]⏎ ⏎ ⏎ {{biotech-stub}} All content in the above text box is licensed under the Creative Commons Attribution-ShareAlike license Version 4 and was originally sourced from https://en.wikipedia.org/w/index.php?diff=prev&oldid=796684599.
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